Planta Medica, Inhaltsverzeichnis Planta Med 1997; 63(6): 550-551DOI: 10.1055/s-2006-957762 Letters © Georg Thieme Verlag Stuttgart · New YorkAcyl-CoA: Cholesterol Acyltransferase Inhibitors from Magnolia obovata Byoung-Mog Kwon1 , Mi-Kyoung Kim1 , Seung-Ho Lee1 , Jeong-Ah Kim2 , Ihn-Rhan Lee2 , Young-Kook Kim1 , Song-Hae Bok1 1Protein Regulator RU, Korea Research Institute of Bioscience & Biotechnology, KIST, P.O. Box 115 Yoosung, Taejon, Korea 305-600 2Ewha Womans University, College of Pharmacy, Seoul, Korea Artikel empfehlen Abstract als PDF herunterladen Artikel einzeln kaufen Abstract In the course of a search for acyl-CoA : cholesterol acyltransferase (ACAT) inhibitors from natural sources, new types of ACAT inhibitors were isolated from the extract of Magnolia obovata leaves, and identified as obovatol, honokiol, and magnolol. The active compounds inhibit rat liver ACAT with IC50 values of 42, 71, and 86 µM, respectively. PDF (176 kb)
